Founder of 111SKIN, Dr. Yannis Alexandrides is a British and American board certified Cosmetic Surgeon specialising in facial reconstructive and restorative surgery. Having trained in the US, He worked in the busiest trauma hospital in the US and dealt with emergency cases on daily basis, which afforded him a wealth of experience and knowledge.

In 2001 he moved with his family to London where he established 111 Harley St., one of London’s most premier clinics, where he was one of the first surgeons to advocate the use of non-surgical procedures. Understanding the need for prevention - not intervention - Dr. Yannis treats his patients with a unique combination of clinical medicine and a holistic approach, achieving their desired goals with the least interventional methods possible.

As a surgeon, his primary goal has always been to ensure the very best results for his patients, and this led him to research formulas that could be used for the reparation of skin trauma, whether from surgery or clinical procedures such as microdermabrasion and lasers. Healing the invisible damage in the skin on a daily basis is the fundamental principle behind the original 111SKIN Reparative range, and today we have five ranges that address specific concerns that are expressed by patients within Dr. Yannis' clinic. He is still heavily involved with new product development based on his clinical observations and medical experience providing patients with the best of 111 Harley St. within their home.


111 Harley St.
111 Harley Street, London, W1G 6AW
0344 692 1111


Endlessly seeking new and innovative ways of improving aesthetics from the inside-out, he became interested in the use of extreme cold on the body. Having first tried the technology on a trip to the US, he was keen to bring cryotherapy back to the UK and meticulously researched the safest and most effective method of delivering its benefits. in 2016, 111CRYO was launched, utilising nitrogen-free, electrically-cooled technology to ensure an enhanced experience.

Dr. Yannis is well-known to be an innovator in the beauty industry, and endeavours to stay at the forefront of aesthetic techniques to guarantee his patients the very best outcomes. In 2018 he created the spa concept SPA/CLINIC by 111SKIN, which is a marriage of powerful skincare, advanced aesthetic methods, and deep medical expertise. SPA/CLINIC is pioneering the medicalisation of spa to offer patients results-driven treatments fused with sensorial experiences within opulent surroundings.

Committed to excellence and striving to offer the most elite, cutting-edge treatments, Dr. Yannis continues to explore, study, and pursue his passion of wellness, medicine, and aesthetics.


After training at the prestigious Albert Einstein Medical Center, he took residency at Jackson Memorial Hospital in Miami (the second largest hospital in the US) where he studied at the University of Miami and specialised in Plastic and Aesthetic Surgery. Here, he worked in extremely complicated cases, acquiring extensive and invaluable knowledge in facial reconstructive surgery. Dr. Yannis then expanded his training to include highly specialised Microsurgery at the University of Pittsburgh Medical Centre, where is formerly held two Fellowships in Microsurgery and Craniofacial Surgery.


  • UK GMC Specialist Plastic Surgery
  • American Board of Plastic Surgery
  • American Society for Aesthetic Plastic Surgery
  • EU Board of Plastic Surgery
  • Greek Board of Plastic Surgery


  • A presentation on how intensity focused ultrasound can be used for measurable non-invasive fat reduction.
  • Angiogenic therapy of the ischemic limb with bFGF: Effects of concentration and frequency
  • Carpal tunnel syndrome in the USA and Sweden: A socio-economedical comparison.
  • Aesthetic CO2 laser surgery: Evaluation of 907 patients.
  • Thermal injuries following TRAM flap breast reconstruction.
  • Our experience with chemotherapeutic agents in the treatment of cancer of the breast.
  • Abdominal Wall Closure following intestinal transplantation.


Dr. Yannis takes the opportunity to use his reconstructive skills to help those without the financial means or access to medicine. He has joined international missions to correct cosmetic abnormalities such as cleft lip and cleft palates, saying that he is “honoured and humbled to utilise his surgical skills to help those who are underprivileged.”

In addition to this, he has supported the following charities by regularly hosting and attending galas and fundraisers:

  • Carers UK
  • CLIC Sargent
  • Cash & Rocket
  • The Gorbachev Foundation
  • The Women’s Empowerment Initiative
  • Make a Wish


Away from the clinic, Dr. Yannis is an ardent fan of being active, from football with his kids to adrenaline sports, practicing what he preaches about a preventative approach to health and beauty. In his downtime, his ideal weekend is island hopping in his beloved home country of Greece with his family, while his cosmopolitan pursuits include collecting modern art – as a surgeon, beauty in all its forms is never too far from his mind.